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Epithelioid Mesothelioma - Histological Subtype

The most common and treatable histological subtype of mesothelioma is epithelioid mesothelioma, which is diagnosed in more than half of all mesothelioma diagnoses.  This subtype of the disease affects epithelial cells, which are found in the epithelium—a tissue lining found throughout the human body in areas that act as a barrier or separation between different body environments.

The skin is such an example of epithelium. Skin helps to separate the body’s exterior from its interior, and epithelial cells can be found within skin tissue. Epithelial cells perform different functions according to their location within the body, including protection, absorption, filtration, excretion, secretion and sensory reception. When viewed under a microscope, epithelial cells have a distinct cube shape and a visible nucleus.

Epithelioid mesothelioma seems to respond more favorably to treatment than the other two histological subtypes. Because of this, cases of biphasic mesothelioma and sarcomatoid mesothelioma are generally associated with a worse prognosis than is epithelioid mesothelioma. However, the actual courses of treatment are often similar among all three versions. It’s important to receive an accurate histological diagnosis so that doctors can prescribe the most effective cancer treatment plan

Related Information: Histological Subtypes of Mesothelioma

  • biphasic mesothelioma
  • sarcomatoid mesothelioma

Related Information: Forms of Mesothelioma

  • About Mesothelioma
  • Pleural Mesothelioma
  • Peritoneal Mesothelioma
  • Pericardial Mesothelioma
  • Mesothelioma of the Tunica Vaginalis
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