Overexpressed Protein Prevalent in Mesothelioma Cells: Study Uncovers Important Link That Could Lead to Targeted Therapies
Researchers from the University of California at San Francisco’s Comprehensive Cancer Center have recently identified a gene that is significantly overexpressed in mesothelioma malignancies. The gene, known as stathmin, has previously been implicated in other forms of cancer that show a similar aggressiveness and chemoresistancy to mesothelioma. Stathmin is important to the regulation of a cell’s architecture: it instructs the cell when to grow, to divide, to develop and to reproduce. Understanding how to control stathmin expression is currently an important part of many different research projects into cancer treatment. By learning more about the role that stathmin plays in the development of malignant mesothelioma, researchers hope to develop novel therapies for the treatment of mesothelioma.